Flavonoids: New Frontier for Immuno-Regulation and Breast Cancer Control.

ABSTRACT: Breast cancer (BC) remains the second most common cause of cancer-related deaths in women in the US, despite advances in detection and treatment. In addition, breast cancer survivors often struggle with long-term treatment related comorbidities. Identifying novel therapies that are effective while minimizing toxicity is critical in curtailing this disease. Flavonoids, a subclass of plant polyphenols, are emerging as promising treatment options for the prevention and treatment of breast cancer. Recent evidence suggests that in addition to anti-oxidant properties, flavonoids can directly interact with proteins, making them ideal small molecules for the modulation of enzymes, transcription factors and cell surface receptors. Of particular interest is the ability of flavonoids to modulate the

SUBMITTER: Sudhakaran M 

PROVIDER: S-EPMC6523469 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature