Efficacy of an orally administered anti-diarrheal probiotic paste (Pro-Kolin Advanced) in dogs with acute diarrhea: A randomized, placebo-controlled, double-blinded clinical study.

ABSTRACT:

Background

Acute diarrhea is a common clinical presentation of dogs. The effect of specific anti-diarrheal probiotic pastes (ADPPs) in the management of acute, uncomplicated diarrhea in dogs is unknown.

Hypothesis

Administration of an ADPP containing Enterococcus faecium 4b1707 will improve the clinical outcome of acute, uncomplicated diarrhea in dogs compared to placebo.

Animals

One hundred forty-eight client-owned dogs with acute diarrhea as the main clinical sign.

Methods

Double-blinded, placebo-controlled, randomized, blocked, multicenter clinical field study conducted at 14 primary care veterinary practices in the United Kingdom and Ireland.

Results

The ADPP was associated with better clinical outcome compared to placebo in dogs with acute, uncompli

SUBMITTER: Nixon SL 

PROVIDER: S-EPMC6524086 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature