Relations between air pollution and vascular development in 5-year old children: a cross-sectional study in the Netherlands.

ABSTRACT:

Background

Air pollution has been shown to promote cardiovascular disease in adults. Possible mechanisms include air pollution induced changes in arterial wall function and structure. Atherosclerotic vascular disease is a lifelong process and childhood exposure may play a critical role. We investigated whether air pollution is related to arterial wall changes in 5-year old children. To this aim, we developed an air pollution exposure methodology including time-weighted activity patterns improving upon epidemiological studies which assess exposure only at residential addresses.

Methods

The study is part of an existing cohort study in which measurements of carotid artery intima-media thickness, carotid artery distensibility, elastic modulus, diastolic and systolic blood pressu

SUBMITTER: Ntarladima AM 

PROVIDER: S-EPMC6524285 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature