Time course of fluid responsiveness in sepsis: the fluid challenge revisiting (FCREV) study.

ABSTRACT:

Background

Fluid challenge (FC) is one of the most common practices in Intensive Care Unit (ICU). The present study aimed to evaluate whether echocardiographic assessment of the response to FC at the end of the infusion or 20 min later could affect the results of the FC.

Methods

This is a prospective, observational, multicenter study including all ICU patients in septic shock requiring a FC of 500 mL crystalloids over 10 min. Fluid responsiveness was defined as a > 15% increase in stroke volume (SV) assessed by velocity-time integral (VTI) measurements at baseline (T₀), at the end of FC (T₁₀), then 10 (T₂₀) and 20 min (T₃₀) after the end of FC.

Results

From May 20, 2014, to January 7, 2016, a total of 143 patients were enrol

SUBMITTER: Roger C 

PROVIDER: S-EPMC6524325 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature