Photocatalytic carbanion generation - benzylation of aliphatic aldehydes to secondary alcohols.

ABSTRACT: We present a redox-neutral method for the photocatalytic generation of carbanions. Benzylic carboxylates are photooxidized by single electron transfer; immediate CO₂ extrusion and reduction of the in situ formed radical yields a carbanion capable of reacting with aliphatic aldehydes as electrophiles giving the Grignard analogous reaction product.

SUBMITTER: Donabauer K 

PROVIDER: S-EPMC6524566 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature