Performance of semi-automated hippocampal subfield segmentation methods across ages in a pediatric sample.

ABSTRACT: Episodic memory function has been shown to depend critically on the hippocampus. This region is made up of a number of subfields, which differ in both cytoarchitectural features and functional roles in the mature brain. Recent neuroimaging work in children and adolescents has suggested that these regions may undergo different developmental trajectories-a fact that has important implications for how we think about learning and memory processes in these populations. Despite the growing research interest in hippocampal structure and function at the subfield level in healthy young adults, comparatively fewer studies have been carried out looking at subfield development. One barrier to studying these questions has been that manual segmentation of hippocampal subfields-considered by many to be t

SUBMITTER: Schlichting ML 

PROVIDER: S-EPMC6524646 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature