FMRI biomarkers of social cognitive skills training in psychosis: Extrinsic and intrinsic functional connectivity.

ABSTRACT: Social cognitive skills training interventions for psychotic disorders have shown improvement in social cognitive performance tasks, but little was known about brain-based biomarkers linked to treatment effects. In this pilot study, we examined whether social cognitive skills training could modulate extrinsic and intrinsic functional connectivity in psychosis using functional magnetic resonance imaging (fMRI). Twenty-six chronic outpatients with psychotic disorders were recruited from either a Social Cognitive Skills Training (SCST) or an activity- and time-matched control intervention. At baseline and the end of intervention (12 weeks), participants completed two social cognitive tasks: a Facial Affect Matching task and a Mental State Attribution Task, as well as resting-state fMRI (rs-fM

SUBMITTER: Lee J 

PROVIDER: S-EPMC6524815 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature