The effect of differential spatiotopic information on the acquisition and generalization of fear of movement-related pain.

ABSTRACT: Fear of movement-related pain significantly contributes to musculoskeletal chronic pain disability. Previous research has shown that fear of movement-related pain can be classically conditioned. That is, in a differential fear conditioning paradigm, after (repeatedly) pairing a neutral joystick movement (conditioned stimulus; CS+) with a painful stimulus (unconditioned stimulus; pain-US), that movement in itself starts to elicit self-reported fear and elevated psychophysiological arousal compared to a control joystick movement (CS-) that was never paired with pain. Further, it has been demonstrated that novel movements that are more similar to the original CS+ elicit more fear than novel movements that are more similar to the CS-, an adaptive process referred to as stimulus generalizati

SUBMITTER: Meulders A 

PROVIDER: S-EPMC6525585 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature