Rapid-Response and Highly Sensitive Boronate Derivative-Based Fluorescence Probe for Detecting H₂O₂ in Living Cells.

ABSTRACT: Intracellular H₂O₂ monitoring is important and has driven researchers to pursue advancements for the rapid identification of H₂O₂, since H₂O₂ is short-lived in cell lines. An arylboronate derivative has been investigated as a chemospecific fluorescence recognition agent for H₂O₂. Triphenylimidazoleoxadiazolephenyl (TPIOP) boronate was contrived as a novel candidate for the rapid and sensitive recognition of H₂O₂. The probe was conjugated using the TPIOP functional group acting as an excellent fluorescent enhancer. The TPIOP group stimulated the polarization of C-B bond due to its extended π-conjugation, which included heteroatoms, and induced the production of rapid signal b

SUBMITTER: Selvaraj M 

PROVIDER: S-EPMC6525842 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature