Primary Mechanism Study of Panax notoginseng Flower (Herb) on Myocardial Infarction in Rats.

ABSTRACT:

Background

Panax notoginseng (Burk.) F. H. Chen is one of the most common herbs in China. Because of its good efficacy and little adverse reaction, Panax notoginseng has been used widely to treat cardiovascular diseases (CVDs).

Objective

To investigate effects of Panax notoginseng flower (PN-F) on rats with myocardial infarction (MI).

Methods

The proximal left anterior descending coronary artery in rats was ligated to induce acute myocardial infarction. Then, animals were randomly assigned to four experimental groups: MI control group, Betaloc control group (with Betaloc 10 mg/kg/d), FD500 (low-dose) group (Panax notoginseng flower decoction 500 mg/kg, n=10), and FD1000 (high-dose) group (Panax notoginseng flower decoction 100

SUBMITTER: Zhou X 

PROVIDER: S-EPMC6525894 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature