LanceletDB: an integrated genome database for lancelet, comparing domain types and combination in orthologues among lancelet and other species.

ABSTRACT: Lancelet (amphioxus) represents the most basally divergent extant chordate (cephalochordates) that diverged from the other two chordate lineages (urochordates and vertebrates) more than half a billion years ago. As it occupies a key position in evolution, it is considered as one of the best proxies for understanding the chordate ancestral state. Thus, the construction of a database with multiple lancelet genomes and gene annotation data, including protein domains, is urgently needed to investigate the loss and gain of domains in orthologues among species, especially ancient domain types (non-vertebrate-specific domains) and novel domain combination, which is helpful for providing new insight into the chordate ancestral state and vertebrate evolution. Here, we present an integrated genome d

SUBMITTER: You L 

PROVIDER: S-EPMC6526094 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature