10-Year Risk Equations for Incident Heart Failure in the General Population.

ABSTRACT:

Background

Primary prevention strategies to mitigate the burden of heart failure (HF) are urgently needed. However, no validated risk prediction tools are currently in use.

Objectives

This study sought to derive 10-year risk equations of developing incident HF.

Methods

Race- and sex-specific 10-year risk equations for HF were derived and validated from individual-level data from 7 community-based cohorts with at least 12 years of follow-up. Participants who were recruited between 1985 and 2000, between 30 to 79 years, and were free of cardiovascular disease at baseline were included to create a pooled cohort (PC) and were randomly split for derivation and internal validation. Model performance was also assessed in 2 additional cohorts.

Results

In the derivation

SUBMITTER: Khan SS 

PROVIDER: S-EPMC6527121 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature