Functional networks underlying item and source memory: shared and distinct network components and age-related differences.

ABSTRACT: Although the medial temporal lobes (MTLs) are critical for both item memory (IM) and source memory (SM), the lateral prefrontal cortex and posterior parietal cortex play a greater role during SM than IM. It is unclear, however, how these differences translate into shared and distinct IM versus SM network components and how these network components vary with age. Within a sample of younger adults (YAs; n = 15, M_age = 19.5 years) and older adults (OAs; n = 40, M_age = 68.6 years), we investigated the functional networks underlying IM and SM. Before functional MRI scanning, participants encoded nouns while making either pleasantness or size judgments. During functional MRI scanning, participants completed IM and SM retrieval tasks. We found that MTL nodes were similarly i

SUBMITTER: Monge ZA 

PROVIDER: S-EPMC6527430 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature