Mental Fatigue and Functional Near-Infrared Spectroscopy (fNIRS) - Based Assessment of Cognitive Performance After Mild Traumatic Brain Injury.

ABSTRACT: Pathological mental fatigue after mild traumatic brain injury (TBI-MF) is characterized by pronounced mental fatigue after cognitive activity. The neurological origin is unknown, and we aimed in the present study to investigate how prolonged mental activity affects cognitive performance and its neural correlates in individuals with TBI-MF. We recruited individuals with TBI-MF (n = 20) at least 5 months after injury, and age-matched healthy controls (n = 20). We used functional near-infrared spectroscopy (fNIRS) to assess hemodynamic changes in the frontal cortex. The self-assessed mental energy level was measured with a visual analog scale (VAS) before and after the experimental procedure. A battery of six neuropsychological tests including Stroop-Simon, Symbol Search, Digit

SUBMITTER: Skau S 

PROVIDER: S-EPMC6527600 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature