Role of Statin Therapy in Primary Prevention of Cardiovascular Disease in Elderly Patients.

ABSTRACT: PURPOSE OF REVIEW:Hypercholesterolemia and statin treatment are nowadays common among people older than 75 years, but clinical heterogeneity in this increasing age group is wide, and treatment decisions may differ from those in younger patients. Aim is to discuss the presentation, modifying factors, and treatment decisions of hypercholesterolemia (usually with statins) in older persons and focusing on primary prevention. RECENT FINDINGS:There are no randomized controlled trials in persons older than 80 years at baseline. Randomized controlled trial findings in younger patients and 75+ subgroups and in observational studies support treatment in secondary prevention of atherosclerotic cardiovascular disease (ASCVD), but trial evidence in primary prevention is less clear. Available data do no

SUBMITTER: Strandberg TE 

PROVIDER: S-EPMC6527904 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature