Dataset Information

Unilateral acute idiopathic maculopathy secondary to yellow fever disease: a case report.

ABSTRACT:

Purpose

To report a case of unilateral acute idiopathic maculopathy (UAIM) associated with yellow fever.

Observations

A 59-year-old man presented with acute blurring of his vision 30 days after symptoms of yellow fever virus infection. Findings resembling unilateral acute idiopathic maculopathy of the left eye were noted on ophthalmoscopy, fluorescein angiography and optical coherence tomography. The right eye exam was normal. He was managed conservatively and recovered complete visual function in 8 weeks.

Conclusions

We describe a case of unilateral acute idiopathic maculopathy disease in a patient infected by yellow fever virus confirmed with reverse transcriptase polymerase chain reaction (RT-PCR).

SUBMITTER: Dompieri RC

PROVIDER: S-EPMC6527946 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Publications

Unilateral acute idiopathic maculopathy secondary to yellow fever disease: a case report.

Dompieri Rodrigo Crispim RC Manzano Roberta Pereira de Almeida RPA Frazão Maria Auxiliadora Monteiro MAM Kurimori Helena Yuri HY Chao John Chii Tyng JCT Lui Aline Cristina Fioravanti ACF

American journal of ophthalmology case reports 20190509

<h4>Purpose</h4>To report a case of unilateral acute idiopathic maculopathy (UAIM) associated with yellow fever.<h4>Observations</h4>A 59-year-old man presented with acute blurring of his vision 30 days after symptoms of yellow fever virus infection. Findings resembling unilateral acute idiopathic maculopathy of the left eye were noted on ophthalmoscopy, fluorescein angiography and optical coherence tomography. The right eye exam was normal. He was managed conservatively and recovered complete v ...[more]

PMID: 31193442

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Project description:BackgroundPurtscher-like retinopathy (PLR) is a rare retinal microangiopathy with unclear pathogenesis. Paracentral acute middle maculopathy (PAMM) is an optical coherence tomography (OCT) sign proposed in recent years, which is characterized by infarction of the middle layer of the retina. This article reported a rare case of PRL and PAMM probably related to improper antihypertensive drug use in a middle-aged male.Case presentationA 49-year-old man presented with a complaint of sudden-onset vision loss and paracentral scotomas in the right eye for approximately 1 week. At presentation, the best-corrected visual acuity (BCVA) was 20/63 OD and 20/20 OS. Fundus examination showed multiple cotton-wool spots and Purtscher flecken in the posterior segment of the right eye. OCT revealed hyper-reflectivities in the inner nuclear layer (INL), consistent with PAMM. En face OCT showed PAMM's characteristic "fern-like" perivenular changes. Fluorescein angiography demonstrated prolonged arm-to-retina time, delayed artery and venous filling, and hypofluorescence corresponding to cotton-wool spots. Examinations of the left eye were unremarkable. Many imaging and laboratory tests were performed to detect the possible cause of PLR and PAMM, but no possible explanation was found except improper antihypertensive drug use. The patient was recommended to stop his antihypertensive medication, and prescribed other systemic medicines, including oral prednisolone (40 mg q.d. with gradual tapering), oral cobalamin (0.5 mg t.i.d.), and subcutaneous injections of compound anisodine (2.0 mL q.d.) beside the superficial temporal artery. Two weeks after onset, his BCVA improved to 20/25 in the right eye. During follow-ups, his BCVA recovered to 20/20, accompanied by the regression of fundus lesions. The patient reported no treatment-related adverse effects.ConclusionThis is the first reported case of PLR and PAMM following improper antihypertensive drug use. Our report expands our understanding of the etiology and pathophysiology of PLR and PAMM. We also stress the importance of proper application of medications in clinical practice.

Dataset Information

Unilateral acute idiopathic maculopathy secondary to yellow fever disease: a case report.

Purpose

Observations

Conclusions

Publications

Unilateral acute idiopathic maculopathy secondary to yellow fever disease: a case report.

Similar Datasets

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