Epidemiology of hepatitis E virus infection in animals in Africa: a systematic review and meta-analysis protocol.

ABSTRACT:

Background

Hepatitis E virus (HEV) is one of the major causes of acute hepatitis in humans worldwide with a case-fatality rate of 1-4% in the general population that might reach 30% in pregnant women. In the past decade in Africa, studies have shown that HEV infects not only humans but also animals. A systematic review summarizing the epidemiological data of HEV has been only performed in humans residing in Africa. We will perform this systematic review and meta-analysis to assess the prevalence of HEV infection in animal species in Africa.

Methods

This review will include cross-sectional studies among different animal species that reported the prevalence of HEV in Africa. We will consider published and unpublished studies from January 1, 2000 to present. A comprehensive sea

SUBMITTER: Modiyinji AF 

PROVIDER: S-EPMC6528234 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature