Candidaemia and a risk predictive model for overall mortality: a prospective multicentre study.

ABSTRACT:

Background

Candidaemia is associated with high mortality. Variables associated with mortality have been published previously, but not developed into a risk predictive model for mortality. We sought to describe the current epidemiology of candidaemia in Australia, analyse predictors of 30-day all-cause mortality, and develop and validate a mortality risk predictive model.

Methods

Adults with candidaemia were studied prospectively over 12 months at eight institutions. Clinical and laboratory variables at time of blood culture-positivity were subject to multivariate analysis for association with 30-day all-cause mortality. A predictive score for mortality was examined by area under receiver operator characteristic curves and a historical data set was used for validation.

Res

SUBMITTER: Keighley C 

PROVIDER: S-EPMC6528341 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature