Prevalence of antibiotic use in a tertiary care hospital in Italy, 2008-2016.

ABSTRACT:

Background

Few data are available about temporal trends of antibiotic use in hospitalized children. The aim of the current study was to investigate the pattern and trends of antibiotic use over the years 2008-2016 in the largest children's hospital in Italy.

Methods

Annual point prevalence surveys of antibiotic use were conducted by reviewing medical charts of 0-17 year-old children hospitalized for ≥48 h. Prevalence of antibiotic use was computed by year, type of ward and indication. Trends in prevalence over time were evaluated using the Cochrane-Armitage test. Possibile determinants of antibiotic use were assessed at univariate analysis and through a logistic regression model.

Results

Out of 3015 children, 1516 (50.3%) received antibiotics, 58.1% of which for medic

SUBMITTER: Ciofi Degli Atti ML 

PROVIDER: S-EPMC6528368 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature