Seasonal influence on TORCH infection and analysis of multi-positive samples with indirect immunofluorescence assay.

ABSTRACT:

Background

TORCH including the pathogens of Toxoplasma gondii (TOX), rubella virus (RV), cytomegalovirus (CMV), and herpes simplex virus (HSV) causes intrauterine infections and poses a worldwide threat to women especially in pregnancy. In this study, we described the seasonal difference in TORCH infection and analyzed the anti-TORCH IgM multipositive serum samples by the indirect immunofluorescence assays (IFA).

Methods

To observe the seasonal influence of the anti-TORCH IgG and IgM antibodies, a retrospective study was conducted with 10 669 women (20-40 y old) before pregnancy from August 2016 to July 2017. Totally 199 ELISA anti-TORCH IgM multipositive serum samples were further tested by IFAs for false-positive analysis.

Results

The prevalence of positive HSV1-IgM

SUBMITTER: Chen L 

PROVIDER: S-EPMC6528586 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature