Natural history of human papillomavirus and vaccinations in men: A literature review.

ABSTRACT:

Background and aims

Infection with high-risk (HR) genotypes of the human papillomavirus (HPV) is necessary for and causative of almost all cervical cancers and their precursor condition, cervical intraepithelial neoplasia. These conditions have been sharply reduced by cervical cytology screening, and a further decrease is expected because of the recent introduction of prophylactic HPV vaccinations. While significant attention has been given to gynecologic HPV disease, men can be affected by HPV-related cancers of the anus, penis, and oropharynx. This literature review aims to address disparities in HPV-related disease in men, and certain HR male subpopulations, compared with women.

Discussion

Overall, immunocompetent men are far less likely than women to develop anogenital H

SUBMITTER: Lieblong BJ 

PROVIDER: S-EPMC6529831 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature