New insights from Opisthorchis felineus genome: update on genomics of the epidemiologically important liver flukes.

ABSTRACT:

Background

The three epidemiologically important Opisthorchiidae liver flukes Opisthorchis felineus, O. viverrini, and Clonorchis sinensis, are believed to harbour similar potencies to provoke hepatobiliary diseases in their definitive hosts, although their populations have substantially different ecogeographical aspects including habitat, preferred hosts, population structure. Lack of O. felineus genomic data is an obstacle to the development of comparative molecular biological approaches necessary to obtain new knowledge about the biology of Opisthorchiidae trematodes, to identify essential pathways linked to parasite-host interaction, to predict genes that contribute to liver fluke pathogenesis and for the effective prevention and control of the disease.

Results

Here we p

SUBMITTER: Ershov NI 

PROVIDER: S-EPMC6530080 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature