Multinational comparison of new antidepressant use in older adults: a cohort study.

ABSTRACT:

Objectives

We used an international pharmacosurveillance network to estimate the rate and characteristics of antidepressant use in older adults in countries with more conservative (UK) and liberal depression guidelines (Canada, USA).

Setting

Electronic health records and population-based administrative data from six jurisdictions in four countries (UK, Taiwan, USA and Canada).

Participants

A historical cohort of older adults (≥65 years) who had a new episode of antidepressant use between 2009 and 2014.

Outcome measures

The age and sex-standardised cumulative incidence of new episodes of antidepressant use in older adults was measured. Descriptive statistics were used to compare the proportion of new users by the antidepressant prescribed, therapeutic class, pot

SUBMITTER: Tamblyn R 

PROVIDER: S-EPMC6530307 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature