Physical heaviness of work and sitting at work as predictors of mortality: a 26-year follow-up of the Helsinki Birth Cohort Study.

ABSTRACT:

Objectives

To examine the relationships of late-career physical heaviness of work and sitting at work with mortality. A national-level job exposure matrix was used to determine the occupation-specific level of physical heaviness and sitting.

Design

Prospective cohort study between years 1990 and 2015.

Setting

Community.

Participants

5210 men and 4725 women from the Helsinki Birth Cohort Study with an occupational code at baseline (ages 45-57 years).

Primary and secondary outcome measures

Total, cardiovascular (International Classification of Diseases 10th Revision I00-I99), cancer (C00-C97) and external (S00-Y84) mortality.

Results

The exposures, physical heaviness and sitting had a non-linear, inverse relationship. During the 26-year follow-up, 1

SUBMITTER: Mikkola TM 

PROVIDER: S-EPMC6530310 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature