Transparency and accuracy in funding investigator-initiated clinical trials: a systematic search in clinical trials databases.

ABSTRACT:

Objectives

This study aims to identify the sources of funding for investigator-initiated clinical trials (IICTs) in Portugal, and to recommend ways to improve the quality of information collected from clinical trial databases about funding.

Design and methods

A systematic search of trial registrations over the last 13 years-using the WHO International Clinical Trials Registry Platform (WHO-ICTRP) and four clinical trials registries (CTRs)-was carried out to identify IICTs in Portugal, used as a case study. Data from the databases were compared with data contained in publications to evaluate the consistency of information on funding sources. The term 'database' is used in this study to refer to both the WHO-ICTRP and the CTRs. When mentioned separately, the WHO-ICTRP is refer

SUBMITTER: Madeira C 

PROVIDER: S-EPMC6530385 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature