Effect of late-life weight change on dementia incidence: a 10-year cohort study using claim data in Korea.

ABSTRACT: BACKGROUND:The association between body mass index (BMI) in late-life and dementia risk remains unclear. We investigated the association between BMI changes over a 2-year period and dementia in an elderly Korean population. METHODS:We examined 67 219 participants aged 60-79 years who underwent BMI measurement in 2002/2003 and 2004/2005 as part of the National Health Insurance Service-Health Screening Cohort. Baseline characteristics including BMI, socioeconomic status and cardiometabolic risk factors were measured at baseline (2002/2003). The difference between BMI at baseline and at the next health screening (2004/2005) was used to calculate the BMI change. After 2 years, the incidence of dementia was monitored for a mean 5.3 years from 2008 to 2013. Multivariate HRs for dementia incidenc

SUBMITTER: Park S 

PROVIDER: S-EPMC6530413 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature