Mcr colistin resistance gene: a systematic review of current diagnostics and detection methods.

ABSTRACT: Resistance to colistin, mediated by chromosomal mutations and more recently, by plasmid-borne mcr genes, is increasingly being reported in bacterial isolates taken from humans, animals, farms, foods, and the environment. To easily identify and contain this quickly spreading menace, efficient diagnostics that are cheaper, faster, simpler, sensitive, and specific have become indispensable and urgently necessary. A thorough and systematic review of the literature available at Pubmed, ScienceDirect and Web of Science was thus undertaken to identify articles describing novel and efficient colistin resistance- and mcr gene-detecting methods. From the final 23 studies included in this review, both phenotypic and molecular tests were found. The phenotypic tests consisted of novel culture media viz

SUBMITTER: Osei Sekyere J 

PROVIDER: S-EPMC6530528 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature