Modeling the joint effects of adolescent and adult PrEP for sexual minority males in the United States.

ABSTRACT:

Background

Pre-exposure prophylaxis (PrEP) is an effective and safe intervention approved for use to prevent HIV transmission. PrEP scale-up strategies and clinical practice are currently being informed by modeling studies, which have estimated the impact of PrEP in adult and adolescent MSM populations separately. This partitioning may miss important effects or yield biased estimates by excluding dependencies between populations.

Methods

We combined two published models of HIV transmission among adults and adolescent MSM. We simulated an HIV epidemic among MSM aged 13-39 without PrEP, with PrEP for adult MSM ages (19-39) and with the addition of PrEP for adolescents ages (16-18), comparing percent of incident infections averted (impact), the number of person-years on PrEP pe

SUBMITTER: Hamilton DT 

PROVIDER: S-EPMC6530873 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature