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ABSTRACT: Introduction
Type 2 diabetes is associated with vascular complications that deteriorate the quality of life and decrease the life expectancy of individuals. We previously reported the efficacy of sitagliptin for glucose control in patients with type 2 diabetes in the Sitagliptin Registration Type 2 Diabetes-Juntendo Collaborating Project (SPIRITS-J). Through the results of the SPIRITS-J study, we expected that optimal comprehensive management of type 2 diabetes according to current clinical practice guidelines in addition to achieving individualized glycemic goals would reduce macrovascular complications and all-cause mortality in Japan. The aim of this study was to evaluate this hypothesis.Methods
We investigated the clinical outcomes prospectively in the extended SPIRITS-
SUBMITTER: Ohmura H
PROVIDER: S-EPMC6531521 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature