Vaccines for preventing anthrax.

ABSTRACT:

Background

Anthrax is a bacterial zoonosis that occasionally causes human disease and is potentially fatal. Anthrax vaccines include a live-attenuated vaccine, an alum-precipitated cell-free filtrate vaccine, and a recombinant protein vaccine.

Objectives

To evaluate the effectiveness, immunogenicity, and safety of vaccines for preventing anthrax.

Search strategy

We searched the following databases (November 2008): Cochrane Infectious Diseases Group Specialized Register; CENTRAL (The Cochrane Library 2008, Issue 4); MEDLINE; EMBASE; LILACS; and mRCT. We also searched reference lists.

Selection criteria

We included randomized controlled trials (RCTs) of individuals and cluster-RCTs comparing anthrax vaccine with placebo, other (non-anthrax) vaccines, or no interv

SUBMITTER: Donegan S 

PROVIDER: S-EPMC6532564 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature