Comparative sensitivity of the MoCA and Mattis Dementia Rating Scale-2 in Parkinson's disease.

ABSTRACT:

Background

Clinicians and researchers commonly use global cognitive assessments to screen for impairment. Currently there are no published studies directly comparing the sensitivity and specificity of the Montreal Cognitive Assessment and Mattis Dementia Rating Scale-2 in PD. The objective of this study was to identify the relative sensitivity and specificity of the Montreal Cognitive Assessment and Mattis Dementia Rating Scale-2 in PD.

Methods

The Montreal Cognitive Assessment and Mattis Dementia Rating Scale-2 were administered to training and validation cohorts. Cutoff scores were determined within the training cohort (n = 85) to optimize sensitivity and specificity for cognitive impairment and were applied to an independent validation cohort (n = 521).

Results

The

SUBMITTER: Hendershott TR 

PROVIDER: S-EPMC6532623 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature