An Allosteric Switch Primes Sequence-Specific DNA Recognition.

ABSTRACT: Regulation of protein-DNA binding specificity occurs through myriad mechanisms. Boudet et al. discover yet a new form of specificity through allosteric regulation, an ATP-induced structural switch that mediates specific DNA recognition in an archaeoeukaryotic primase.

SUBMITTER: Walker MJ 

PROVIDER: S-EPMC6532627 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature