Development and validation of the PET-CT score for diagnosis of malignant pleural effusion.

ABSTRACT:

Purpose

Although some parameters of positron emission tomography with ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) and computed tomography (PET-CT) are somehow helpful in differentiating malignant pleural effusion (MPE) from benign effusions, no individual parameter offers sufficient evidence for its implementation in the clinical practice. The aim of this study was to establish the diagnostic accuracy of a scoring system based on PET-CT (the PET-CT score) in diagnosing MPE.

Methods

One prospective derivation cohort of patients with pleural effusions (84 malignant and 115 benign) was used to develop the PET-CT score for the differential diagnosis of malignant pleural effusion. The PET-CT score was then validated in another independent prospective cohort (n = 74).

SUBMITTER: Yang MF 

PROVIDER: S-EPMC6533224 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature