Perioperative PET/CT lymphoscintigraphy and fluorescent real-time imaging for sentinel lymph node mapping in early staged colon cancer.

ABSTRACT:

Purpose

Using current optical imaging techniques and gamma imaging modalities, perioperative sentinel lymph node (SLN) identification in colon cancer can be difficult when the SLN is located near the primary tumour or beneath a thick layer of (fat) tissue. Sentinel lymph node mapping using PET/CT lymphoscintigraphy combined with real-time visualization of the SLN using near-infrared imaging has shown promising results in several types of cancer and may facilitate the successful identification of the number and location of the SLN in early colon cancer.

Methods

Clinical feasibility of PET/CT lymphoscintigraphy using preoperative endoscopically injected [⁸⁹Zr]Zr-Nanocoll and intraoperative injection of the near-infrared (NIR) tracer Indocyanine Green (ICG) was evalu

SUBMITTER: Ankersmit M 

PROVIDER: S-EPMC6533411 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature