Describing organ dysfunction in the intensive care unit: a cohort study of 20,000 patients.

ABSTRACT:

Background

Multiple organ dysfunction is a common cause of morbidity and mortality in intensive care units (ICUs). Original development of the Sequential Organ Failure Assessment (SOFA) score was not to predict outcome, but to describe temporal changes in organ dysfunction in critically ill patients. Organ dysfunction scoring may be a reasonable surrogate outcome in clinical trials but further exploration of the impact of case mix on the temporal sequence of organ dysfunction is required. Our aim was to compare temporal changes in SOFA scores between hospital survivors and non-survivors.

Methods

We performed a population-based observational retrospective cohort study of critically ill patients admitted from January 1, 2004, to December 31, 2013, to 4 multisystem adult intens

SUBMITTER: Soo A 

PROVIDER: S-EPMC6533687 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature