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Head-to-head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease.

ABSTRACT:

SUBMITTER: Threapleton CJ

PROVIDER: S-EPMC6534184 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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Head-to-head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease.

Threapleton Christopher Jd CJ Janjua Sadia S Fortescue Rebecca R Baker Emma H EH

The Cochrane database of systematic reviews 20190524

<h4>Background</h4>Chronic obstructive pulmonary disease (COPD; including chronic bronchitis and emphysema) is a chronic respiratory condition characterised by shortness of breath, cough and recurrent exacerbations. Long-term antibiotic use may reduce both bacterial load and inflammation in the airways. Studies have shown a reduction of exacerbations with antibiotics in comparison to placebo in people with COPD, but there are concerns about antibiotic resistance and safety.<h4>Objectives</h4>To ...[more]

PMID: 31125127

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