NetPyNE, a tool for data-driven multiscale modeling of brain circuits.

ABSTRACT: Biophysical modeling of neuronal networks helps to integrate and interpret rapidly growing and disparate experimental datasets at multiple scales. The NetPyNE tool (www.netpyne.org) provides both programmatic and graphical interfaces to develop data-driven multiscale network models in NEURON. NetPyNE clearly separates model parameters from implementation code. Users provide specifications at a high level via a standardized declarative language, for example connectivity rules, to create millions of cell-to-cell connections. NetPyNE then enables users to generate the NEURON network, run efficiently parallelized simulations, optimize and explore network parameters through automated batch runs, and use built-in functions for visualization and analysis - connectivity matrices, voltage traces, s

SUBMITTER: Dura-Bernal S 

PROVIDER: S-EPMC6534378 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature