Osteochondral Graft Size Is Significantly Associated With Increased Force and Decreased Chondrocyte Viability.

ABSTRACT:

Background

Insertion force has been shown to significantly reduce chondrocyte viability during osteochondral allograft transplantation. How graft size influences the required insertion force and chondrocyte viability has yet to be determined. Hypothesis/Purpose: The purpose was to characterize how graft size influences insertion force requirements and chondrocyte viability during osteochondral transplantation. The hypothesis was that larger grafts would require greater force and reduce chondrocyte viability.

Study design

Controlled laboratory study.

Methods

Four graft sizes-15 × 5 mm, 15 × 10 mm, 25 × 5 mm, and 25 × 10 mm (diameter × depth)-were harvested from 13 thawed fresh-frozen human cadaveric distal femurs. Average, maximum, and cumulative force and number of im

SUBMITTER: Walczak BE 

PROVIDER: S-EPMC6534416 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature