Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia differ from patients with asthma.

ABSTRACT:

Background

Bronchopulmonary dysplasia (BPD) is a risk factor for respiratory disease in adulthood. Despite the differences in underlying pathology, patients with a history of BPD are often treated as asthmatics. We hypothesized that pulmonary outcomes and health-related quality of life (HRQoL) were different in adults born preterm with and without a history of BPD compared to asthmatics and healthy individuals.

Methods

We evaluated 96 young adults from the LUNAPRE cohort ( clinicaltrials.gov/ct2/show/NCT02923648 ), including 26 individuals born preterm with a history of BPD (BPD), 23 born preterm without BPD (preterm), 23 asthmatics and 24 healthy controls. Extensive lung function testing and HRQoL were assessed.

Results

The BPD group had more severe airway obstructio

SUBMITTER: Um-Bergstrom P 

PROVIDER: S-EPMC6534852 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature