Association of breast and gut microbiota dysbiosis and the risk of breast cancer: a case-control clinical study.

ABSTRACT:

Background

Breast cancer ranks first in women, and is the second cause of death in this gender. In addition to genetics, the environment contributes to the development of the disease, although the factors involved are not well known. Among the latter is the influence of microorganisms and, therefore, attention is recently being paid to the mammary microbiota. We hypothesize that the risk of breast cancer could be associated with the composition and functionality of the mammary/gut microbiota, and that exposure to environmental contaminants (endocrine disruptors, EDCs) might contribute to alter these microbiota.

Methods

We describe a case-control clinical study that will be performed in women between 25 and 70 years of age. Cases will be women diagnosed and surgically interve

SUBMITTER: Plaza-Diaz J 

PROVIDER: S-EPMC6534876 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature