Intravoxel incoherent motion perfusion in patients with Moyamoya disease: comparison with ¹⁵O-gas positron emission tomography.

ABSTRACT:

Background

Intravoxel incoherent motion magnetic resonance imaging (IVIM) enables non-invasive measurement of brain perfusion.

Purpose

To investigate whether IVIM could be used to evaluate the hemodynamic disturbance of Moyamoya disease (MMD) by comparison with the gold-standard ¹⁵O-gas positron emission tomography (PET) method.

Material and methods

Ten consecutive patients with MMD (six women; mean age = 42.8 years) and 10 age-matched healthy controls were evaluated by diffusion-weighted images with 12 different b values in the range of 0-900 s/mm² and ¹⁵O-gas PET. Tomographic maps of IVIM parameters, perfusion fraction (f ), pseudo-diffusion coefficient (D*), and f・D*, as well as cerebral blood volume (CBV

SUBMITTER: Hara S 

PROVIDER: S-EPMC6535913 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature