Comparative modeling of transcranial magnetic and electric stimulation in mouse, monkey, and human.

ABSTRACT: Transcranial magnetic stimulation (TMS) and transcranial electric stimulation (TES) are increasingly popular methods to noninvasively affect brain activity. However, their mechanism of action and dose-response characteristics remain under active investigation. Translational studies in animals play a pivotal role in these efforts due to a larger neuroscientific toolset enabled by invasive recordings. In order to translate knowledge gained in animal studies to humans, it is crucial to generate comparable stimulation conditions with respect to the induced electric field in the brain. Here, we conduct a finite element method (FEM) modeling study of TMS and TES electric fields in a mouse, capuchin and macaque monkeys, and a human model. We systematically evaluate the induced electric fields and

SUBMITTER: Alekseichuk I 

PROVIDER: S-EPMC6536349 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature