Sociodemographic, health behavioral, and clinical risk factors for anotia/microtia in a population-based case-control study.

ABSTRACT:

Objective

Anotia and microtia are congenital malformations of the external ear with few known risk factors. We conducted a comprehensive assessment of a wide range of potential risk factors using data from the National Birth Defects Prevention Study (NBDPS), a population-based case-control study of non-chromosomal structural birth defects in the United States.

Methods

Mothers of 699 infants with anotia or microtia (cases) and 11,797 non-malformed infants (controls) delivered between 1997 and 2011 were interviewed to obtain information about sociodemographic, health behavioral, and clinical characteristics. Adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were estimated with logistic regression.

Results

Infants with anotia/microtia were more likely to be

SUBMITTER: Ryan MA 

PROVIDER: S-EPMC6536360 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature