Co-expression network analysis identifies gonad- and embryo-associated protein modules in the sentinel species Gammarus fossarum.

ABSTRACT: Next generation sequencing and mass spectrometry technologies have recently expanded the availability of whole transcriptomes and proteomes beyond classical model organisms in molecular biology, even in absence of an annotated genome. However, the fragmented nature of transcriptomic and proteomic data reduces the ability to interpret the data, notably in non-model organisms. Network-based approaches may help extracting important biological information from -omics datasets. The reproductive cycle of the freshwater crustacean Gammarus fossarum.provides an excellent case study to test the relevance of a network analysis in non-model organisms. Here, we illustrated how the use of a co-expression network analysis (based on Weighted Gene Co-expression Network Analysis algorithm, WGCNA) allowed i

SUBMITTER: Degli Esposti D 

PROVIDER: S-EPMC6536538 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature