Clinical Experience with Tigecycline in the Treatment of Prosthetic Joint Infections.

ABSTRACT: Purpose: The purpose of this study was to examine the use of tigecycline in the treatment of prosthetic joint infection (PJI). Methods: This is a retrospective review performed from 2008 to 2017, examining adult patients with PJI at a tertiary medical referral center who received tigecycline for 75% or greater of the treatment course. Failure was defined as need to return to the operating room for an infectious complication or persistent drainage from the joint. Results: A total of 37 patients met inclusion criteria. The median age was 65 years, and 65% of patients were female. The most common reasons for tigecycline use were culture negative infection, polymicrobial infection, and renal failure, but other reasons included antimicrobial allergies and resistant organism

SUBMITTER: Lastinger A 

PROVIDER: S-EPMC6536800 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature