Network-level connectivity is a critical feature distinguishing dystonic tremor and essential tremor.

ABSTRACT: Dystonia is a movement disorder characterized by involuntary muscle co-contractions that give rise to disabling movements and postures. A recent expert consensus labelled the incidence of tremor as a core feature of dystonia that can affect body regions both symptomatic and asymptomatic to dystonic features. We are only beginning to understand the neural network-level signatures that relate to clinical features of dystonic tremor. At the same time, clinical features of dystonic tremor can resemble that of essential tremor and present a diagnostic confound for clinicians. Here, we examined network-level functional activation and connectivity in patients with dystonic tremor and essential tremor. The dystonic tremor group included primarily cervical dystonia patients with dystonic head tremo

SUBMITTER: DeSimone JC 

PROVIDER: S-EPMC6536846 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature