Reduced hippocampal subfield volumes and memory function in school-aged children born preterm with very low birthweight (VLBW).

ABSTRACT:

Background

The hippocampus, an essential structure for learning and memory, has a reduced volume in preterm born (gestational age < 37 weeks) individuals with very low birth weight (VLBW: birth weight < 1500 g), which may affect memory function. However, the hippocampus is a complex structure with distinct subfields related to specific memory functions. These subfields are differentially affected by a variety of neuropathological conditions, but it remains unclear how these subfields may be affected by medical complications following preterm birth which may cause aberrant brain development, and the consequences of this on learning and memory function in children with VLBW.

Methods

Children born preterm with VLBW (n = 34) and term-born controls from the Norwegian Mother and C

SUBMITTER: Aanes S 

PROVIDER: S-EPMC6536855 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature