Lipid levels and the risk of hemorrhagic stroke among women.

ABSTRACT:

Objective

To examine the association between lipid levels and hemorrhagic stroke risk among women.

Methods

We performed a prospective cohort study among 27,937 women enrolled in the Women's Health Study with measured total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C), as well as triglycerides. Strokes were confirmed by medical record review. We used Cox proportional hazards models to analyze associations between lipid categories and hemorrhagic stroke risk.

Results

During a mean of 19.3 years of follow-up, 137 hemorrhagic strokes occurred. Compared to those with LDL-C levels 100-129.9 mg/dL, after multivariable adjustment, those with LDL-C levels <70 mg/dL had 2.17 times the risk (95% confidence interval [C

SUBMITTER: Rist PM 

PROVIDER: S-EPMC6537127 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature