Procalcitonin levels in candidemia versus bacteremia: a systematic review.

ABSTRACT:

Background

Procalcitonin (PCT) is a biomarker used to assess systemic inflammation, infection, and sepsis and to optimize antimicrobial therapies. Its role in the in the differential diagnosis between candidemia and bacteremia is unclear. The aim of this systematic review was to summarize the current evidence about PCT values for differentiating candidemia from bacteremia.

Methods

PubMed and EMBASE were searched for studies reporting data on the diagnostic performance of serum PCT levels in intensive care unit (ICU) or non-ICU adult patients with candidemia, in comparison to patients with bacteremia.

Results

We included 16 studies for a total of 45.079 patients and 785 cases of candidemia. Most studies claimed to report data relating to the use of PCT values for diffe

SUBMITTER: Cortegiani A 

PROVIDER: S-EPMC6537202 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature