Utility of CT assessment in hematology patients with invasive aspergillosis: a post-hoc analysis of phase 3 data.

ABSTRACT:

Background

Pulmonary computed tomography (CT) scans are commonly used as part of the clinical criteria in diagnostic workup of invasive fungal diseases like invasive aspergillosis, and may identify radiographic abnormalities, such as halo signs or air-crescent signs. We assessed the diagnostic utility of CT assessment in patients with hematologic malignancies or those who had undergone allogeneic hematopoietic stem cell transplantation in whom invasive aspergillosis was suspected.

Methods

This post-hoc analysis assessed data from a prospective, multicenter, international trial of voriconazole (with and without anidulafungin) in patients with suspected invasive aspergillosis (IA; proven, probable, or possible, using 2008 European Organisation for Research and Treatment of Can

SUBMITTER: Jin J 

PROVIDER: S-EPMC6537389 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature